| Item Type | Name |
|
Concept
|
Acute Disease
|
|
Concept
|
Action Potentials
|
|
Concept
|
Administration, Topical
|
|
Concept
|
Adrenergic alpha-Agonists
|
|
Concept
|
Acclimatization
|
|
Concept
|
Adenosine
|
|
Concept
|
Adenosine Diphosphate
|
|
Concept
|
Adrenergic alpha-Antagonists
|
|
Concept
|
Aged, 80 and over
|
|
Concept
|
Air Pollutants
|
|
Concept
|
Aldosterone
|
|
Concept
|
Atmospheric Pressure
|
|
Concept
|
Asparagine
|
|
Concept
|
Anesthesia, Local
|
|
Concept
|
Acetylcholine
|
|
Concept
|
Acetylcholinesterase
|
|
Concept
|
Adaptation, Physiological
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Acetylcysteine
|
|
Concept
|
Aged
|
|
Concept
|
Biphenyl Compounds
|
|
Concept
|
Boron Compounds
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Adrenal Cortex
|
|
Concept
|
Calcium Channel Agonists
|
|
Concept
|
Cats
|
|
Concept
|
Hypoxia, Brain
|
|
Concept
|
Cerebral Cortex
|
|
Concept
|
Anaerobiosis
|
|
Concept
|
Anesthesia
|
|
Concept
|
Aorta
|
|
Concept
|
Calpain
|
|
Concept
|
Aminoquinolines
|
|
Concept
|
Antioxidants
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Arginine
|
|
Concept
|
Apnea
|
|
Concept
|
Benzazepines
|
|
Concept
|
Carotid Body
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Cerebrovascular Circulation
|
|
Concept
|
Cervical Plexus
|
|
Concept
|
Aspartic Acid
|
|
Concept
|
Atropine
|
|
Concept
|
Digoxin
|
|
Concept
|
Autoradiography
|
|
Concept
|
Chloralose
|
|
Concept
|
Cholera Toxin
|
|
Concept
|
Cadmium
|
|
Concept
|
Biophysics
|
|
Concept
|
Body Temperature
|
|
Concept
|
Barium
|
|
Concept
|
Benzylamines
|
|
Concept
|
Bicarbonates
|
|
Concept
|
Body Weight
|
|
Concept
|
Butaclamol
|
|
Concept
|
Brain
|
|
Concept
|
Carbonic Anhydrases
|
|
Concept
|
Carotid Arteries
|
|
Concept
|
Cattle
|
|
Concept
|
Brain Stem
|
|
Concept
|
Capsaicin
|
|
Concept
|
Central Nervous System
|
|
Concept
|
Cerebellum
|
|
Concept
|
Chemotaxis
|
|
Concept
|
Chicago
|
|
Concept
|
Blood Gas Analysis
|
|
Concept
|
Blood Pressure Determination
|
|
Concept
|
gamma-Aminobutyric Acid
|
|
Concept
|
Cold Temperature
|
|
Concept
|
Caffeine
|
|
Concept
|
Carotid Sinus
|
|
Concept
|
Glutamate Decarboxylase
|
|
Concept
|
Guinea Pigs
|
|
Concept
|
HEPES
|
|
Concept
|
Diabetes Mellitus, Type 2
|
|
Concept
|
Cysteine
|
|
Concept
|
Hydroxylation
|
|
Concept
|
Dithionite
|
|
Concept
|
Cyanides
|
|
Concept
|
Domperidone
|
|
Concept
|
Cranial Nerves
|
|
Concept
|
Cytoskeleton
|
|
Concept
|
Dose-Response Relationship, Radiation
|
|
Concept
|
Dogs
|
|
Concept
|
Isoproterenol
|
|
Concept
|
Laboratory Animal Science
|
|
Concept
|
Electrophysiology
|
|
Concept
|
Endoplasmic Reticulum
|
|
Concept
|
Hypoglossal Nerve
|
|
Concept
|
Chromatography, High Pressure Liquid
|
|
Concept
|
Clonidine
|
|
Concept
|
Erythropoietin
|
|
Concept
|
Ethylmaleimide
|
|
Concept
|
Dantrolene
|
|
Concept
|
Dipyridamole
|
|
Concept
|
Metalloporphyrins
|
|
Concept
|
Indoles
|
|
Concept
|
Egtazic Acid
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Dendrites
|
|
Concept
|
Cyclic GMP
|
|
Concept
|
Hippocampus
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Lobeline
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Erythropoiesis
|
|
Concept
|
Genetics, Medical
|
|
Concept
|
Heme
|
|
Concept
|
Maleimides
|
|
Concept
|
Ketanserin
|
|
Concept
|
Methysergide
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Virulence Factors, Bordetella
|
|
Concept
|
Phenylephrine
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Models, Cardiovascular
|
|
Concept
|
Poly(ADP-ribose) Polymerases
|
|
Concept
|
Potassium Chloride
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Indazoles
|
|
Concept
|
Glycolysis
|
|
Concept
|
Oxadiazoles
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Middle Aged
|
|
Concept
|
Rats, Inbred SHR
|
|
Concept
|
Receptors, Angiotensin
|
|
Concept
|
Respiratory Center
|
|
Concept
|
Molecular Biology
|
|
Concept
|
Muscimol
|
|
Concept
|
Hot Temperature
|
|
Concept
|
Ion Channels
|
|
Concept
|
Neural Tube Defects
|
|
Concept
|
Nerve Block
|
|
Concept
|
Synaptic Transmission
|
|
Concept
|
Nobel Prize
|
|
Concept
|
Lidocaine
|
|
Concept
|
Mitochondria, Heart
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Physiology
|
|
Concept
|
Naloxone
|
|
Concept
|
Nitrites
|
|
Concept
|
Nitroprusside
|
|
Concept
|
Oxygen
|
|
Concept
|
Sulpiride
|
|
Concept
|
Periodicity
|
|
Concept
|
Protein Binding
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Pulmonary Gas Exchange
|
|
Concept
|
Glossopharyngeal Nerve
|
|
Concept
|
Glutamates
|
|
Concept
|
Glycine
|
|
Concept
|
Regional Blood Flow
|
|
Concept
|
Heart Defects, Congenital
|
|
Concept
|
Rabbits
|
|
Concept
|
Pons
|
|
Concept
|
Intestine, Small
|
|
Concept
|
Potassium Channels
|
|
Concept
|
Rats, Inbred WKY
|
|
Concept
|
Receptors, Adrenergic, alpha
|
|
Concept
|
Serotonin
|
|
Concept
|
Swine
|
|
Concept
|
Telemetry
|
|
Concept
|
Hemoglobins, Abnormal
|
|
Concept
|
Sodium Cyanide
|
|
Concept
|
Sulfites
|
|
Concept
|
Sympathectomy
|
|
Concept
|
Humans
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Protein Biosynthesis
|
|
Concept
|
Superoxides
|
|
Concept
|
Intracellular Membranes
|
|
Concept
|
Electron Transport Complex III
|
|
Concept
|
United States
|
|
Concept
|
Vagotomy
|
|
Concept
|
Ion Transport
|
|
Concept
|
Vertebral Artery
|
|
Concept
|
Calcium Channels
|
|
Concept
|
Neprilysin
|
|
Concept
|
Echocardiography, Doppler
|
|
Concept
|
Sodium Channels
|
|
Concept
|
Nicotinic Agonists
|
|
Concept
|
Cell Respiration
|
|
Concept
|
Cytochrome P-450 CYP11B2
|
|
Concept
|
Excitatory Postsynaptic Potentials
|
|
Concept
|
Vagus Nerve
|
|
Concept
|
Valine
|
|
Concept
|
Wakefulness
|
|
Concept
|
2-Amino-5-phosphonovalerate
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Baltimore
|
|
Concept
|
Lipid Peroxidation
|
|
Concept
|
PC12 Cells
|
|
Concept
|
Ion Channel Gating
|
|
Concept
|
Mitochondria
|
|
Concept
|
Second Messenger Systems
|
|
Concept
|
Proto-Oncogene Proteins c-fos
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Cyclic AMP Response Element-Binding Protein
|
|
Concept
|
Quisqualic Acid
|
|
Concept
|
Medulla Oblongata
|
|
Concept
|
NADH Dehydrogenase
|
|
Concept
|
Apoptosis
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Solitary Nucleus
|
|
Concept
|
Excitatory Amino Acid Antagonists
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Cadmium Chloride
|
|
Concept
|
Mole Rats
|
|
Concept
|
Brain-Derived Neurotrophic Factor
|
|
Concept
|
Staurosporine
|
|
Concept
|
Kv1.1 Potassium Channel
|
|
Concept
|
Protein Transport
|
|
Concept
|
Calcium Signaling
|
|
Concept
|
Cross-Over Studies
|
|
Concept
|
CpG Islands
|
|
Concept
|
Myosin Heavy Chains
|
|
Concept
|
Nodose Ganglion
|
|
Concept
|
Receptors, Dopamine D1
|
|
Concept
|
Calcium Channels, T-Type
|
|
Concept
|
Calcium Channels, N-Type
|
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
|
Concept
|
Adrenergic alpha-2 Receptor Agonists
|
|
Concept
|
Pertussis Toxin
|
|
Concept
|
Carboxypeptidase H
|
|
Concept
|
Systems Biology
|
|
Concept
|
E1A-Associated p300 Protein
|
|
Concept
|
Receptor, Angiotensin, Type 1
|
|
Concept
|
Ether-A-Go-Go Potassium Channels
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Chloride Channels
|
|
Concept
|
Receptors, Adrenergic, alpha-2
|
|
Concept
|
Muscarinic Agonists
|
|
Concept
|
Ryanodine Receptor Calcium Release Channel
|
|
Concept
|
Response Elements
|
|
Concept
|
6-Cyano-7-nitroquinoxaline-2,3-dione
|
|
Concept
|
Transcription Factor AP-1
|
|
Concept
|
Amino Acid Motifs
|
|
Concept
|
Phrenic Nerve
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Aryl Hydrocarbon Receptor Nuclear Translocator
|
|
Concept
|
Receptors, Dopamine
|
|
Concept
|
Receptors, Nicotinic
|
|
Concept
|
Rats, Inbred Strains
|
|
Concept
|
Reserpine
|
|
Concept
|
Serine
|
|
Concept
|
Sodium Chloride
|
|
Concept
|
Calcium-Calmodulin-Dependent Protein Kinase Type 2
|
|
Concept
|
Electron Transport Complex I
|
|
Concept
|
Biomedical Research
|
|
Concept
|
Cathepsin L
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
Rats
|
|
Concept
|
Proteolysis
|
|
Concept
|
Nitric Oxide Synthase Type II
|
|
Concept
|
Insulin-Secreting Cells
|
|
Concept
|
Temperature
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Hypoxia-Inducible Factor 1
|
|
Concept
|
Proto-Oncogene Proteins c-jun
|
|
Concept
|
Blotting, Northern
|
|
Concept
|
Sodium Bicarbonate
|
|
Concept
|
Cell Hypoxia
|
|
Concept
|
N-Methylaspartate
|
|
Concept
|
Proto-Oncogene Proteins p21(ras)
|
|
Concept
|
Antisense Elements (Genetics)
|
|
Concept
|
Anesthetics, Intravenous
|
|
Concept
|
DNA Methylation
|
|
Concept
|
GTP-Binding Proteins
|
|
Concept
|
Calcium-Calmodulin-Dependent Protein Kinases
|
|
Concept
|
omega-Conotoxin GVIA
|
|
Concept
|
Hypoxia-Ischemia, Brain
|
|
Concept
|
Secretory Vesicles
|
|
Concept
|
Muscarinic Antagonists
|
|
Concept
|
Cation Transport Proteins
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
omega-Conotoxins
|
|
Concept
|
p300-CBP Transcription Factors
|
|
Concept
|
Adrenergic alpha-2 Receptor Antagonists
|
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
|
Concept
|
Cell Cycle Checkpoints
|
|
Concept
|
Transcriptome
|
|
Concept
|
KATP Channels
|
|
Concept
|
Angiotensin Receptor Antagonists
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Receptor, Endothelin A
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Imidazoline Receptors
|
|
Concept
|
Aminophylline
|
|
Concept
|
Anesthesia, General
|
|
Concept
|
Biguanides
|
|
Concept
|
Calcium
|
|
Concept
|
Calcium Channel Blockers
|
|
Concept
|
Calcium-Binding Proteins
|
|
Concept
|
Brain Ischemia
|
|
Concept
|
Data Interpretation, Statistical
|
|
Concept
|
Electrochemistry
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Epinephrine
|
|
Concept
|
Intercellular Junctions
|
|
Concept
|
Kinetics
|
|
Concept
|
Lysine
|
|
Concept
|
Membrane Potentials
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Nicotine
|
|
Concept
|
Norepinephrine
|
|
Concept
|
Protoporphyrins
|
|
Concept
|
Receptors, Adrenergic, beta
|
|
Concept
|
Recurrent Laryngeal Nerve
|
|
Concept
|
Spinal Cord
|
|
Concept
|
Sulfides
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
Dopamine Antagonists
|
|
Concept
|
Computational Biology
|
|
Concept
|
Nitroarginine
|
|
Concept
|
Calcium Channels, L-Type
|
|
Concept
|
Genomics
|
|
Concept
|
Potassium Channels, Voltage-Gated
|
|
Concept
|
Databases, Nucleic Acid
|
|
Academic Article
|
Heterogeneity in cytosolic calcium responses to hypoxia in carotid body cells.
|
|
Academic Article
|
Cell selective induction and transcriptional activation of immediate early genes by hypoxia.
|
|
Academic Article
|
Carbon monoxide and carotid body chemoreception.
|
|
Academic Article
|
Possible genomic mechanism involved in control systems responses to hypoxia.
|
|
Academic Article
|
Regulation of neuronal nitric oxide synthase gene expression by hypoxia. Role of nitric oxide in respiratory adaptation to low pO2.
|
|
Academic Article
|
G proteins in carotid body chemoreception.
|
|
Academic Article
|
Carotid body I1-imidazoline receptors: binding, visualization and modulatory function.
|
|
Academic Article
|
Activation of nitric oxide synthase gene expression by hypoxia in central and peripheral neurons.
|
|
Academic Article
|
NO and CO as second messengers in oxygen sensing in the carotid body.
|
|
Academic Article
|
Nitric oxide and ventilatory response to hypoxia.
|
|
Academic Article
|
Norepinephrine inhibits a toxin resistant Ca2+ current in carotid body glomus cells: evidence for a direct G protein mechanism.
|
|
Academic Article
|
Involvement of substance P in neutral endopeptidase modulation of carotid body sensory responses to hypoxia.
|
|
Academic Article
|
Ca2+ current in rabbit carotid body glomus cells is conducted by multiple types of high-voltage-activated Ca2+ channels.
|
|
Academic Article
|
Induction of immediate early response genes by hypoxia. Possible molecular bases for systems adaptation to low pO2.
|
|
Academic Article
|
Dual influence of nitric oxide on gene regulation during hypoxia.
|
|
Academic Article
|
Oxygen sensing by the carotid body chemoreceptors.
|
|
Academic Article
|
Intracellular pathways linking hypoxia to activation of c-fos and AP-1.
|
|
Academic Article
|
Release of dopamine and norepinephrine by hypoxia from PC-12 cells.
|
|
Academic Article
|
Endogenous carbon monoxide in control of respiration.
|
|
Academic Article
|
Nitric oxide inhibits L-type Ca2+ current in glomus cells of the rabbit carotid body via a cGMP-independent mechanism.
|
|
Academic Article
|
HERG-Like potassium current regulates the resting membrane potential in glomus cells of the rabbit carotid body.
|
|
Academic Article
|
Role of substance P in neutral endopeptidase modulation of hypoxic response of the carotid body.
|
|
Academic Article
|
Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression.
|
|
Academic Article
|
Selected Contribution: Improved anoxic tolerance in rat diaphragm following intermittent hypoxia.
|
|
Academic Article
|
Neural drives and breathing stability.
|
|
Academic Article
|
CO2/HCO3- modulates K+ and Ca2+ currents in glomus cells of the carotid body.
|
|
Academic Article
|
Chronic intermittent hypoxia enhances carotid body chemoreceptor response to low oxygen.
|
|
Academic Article
|
Neurotransmitter release from the rabbit carotid body: differential effects of hypoxia on substance P and acetylcholine release.
|
|
Academic Article
|
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha.
|
|
Academic Article
|
Sleep apneas: an oxidative stress?
|
|
Academic Article
|
Blunted respiratory responses to hypoxia in mutant mice deficient in nitric oxide synthase-3.
|
|
Academic Article
|
The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation.
|
|
Academic Article
|
Ventilatory changes during intermittent hypoxia: importance of pattern and duration.
|
|
Academic Article
|
Cellular mechanisms of oxygen sensing at the carotid body: heme proteins and ion channels.
|
|
Academic Article
|
Augmentation of L-type calcium current by hypoxia in rabbit carotid body glomus cells: evidence for a PKC-sensitive pathway.
|
|
Academic Article
|
Intermittent hypoxia: cell to system.
|
|
Academic Article
|
Oxygen sensing during intermittent hypoxia: cellular and molecular mechanisms.
|
|
Academic Article
|
Mutant mice deficient in NOS-1 exhibit attenuated long-term facilitation and short-term potentiation in breathing.
|
|
Academic Article
|
Peripheral and central chemosensitivity: multiple mechanisms, multiple sites? A workshop summary.
|
|
Academic Article
|
Chemoreceptor responses to substance P, physalaemin and eledoisin: evidence for neurokinin-1 receptors in the cat carotid body.
|
|
Academic Article
|
Tachykinins in the control of breathing by hypoxia: pre- and post-genomic era.
|
|
Academic Article
|
Gene regulation during intermittent hypoxia: evidence for the involvement of reactive oxygen species.
|
|
Academic Article
|
Reactive oxygen species in the plasticity of respiratory behavior elicited by chronic intermittent hypoxia.
|
|
Academic Article
|
Release of substance P by low oxygen in the rabbit carotid body: evidence for the involvement of calcium channels.
|
|
Academic Article
|
Systemic and cellular responses to intermittent hypoxia: evidence for oxidative stress and mitochondrial dysfunction.
|
|
Academic Article
|
Peripheral chemoreceptors in health and disease.
|
|
Academic Article
|
Oxidative stress in the systemic and cellular responses to intermittent hypoxia.
|
|
Academic Article
|
Entrainment pattern between sympathetic and phrenic nerve activities in the Sprague-Dawley rat: hypoxia-evoked sympathetic activity during expiration.
|
|
Academic Article
|
Hypoxia does not uniformly facilitate the release of multiple transmitters from the carotid body.
|
|
Academic Article
|
Functional role of substance P for respiratory control during development.
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Academic Article
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CO(2) and pH independently modulate L-type Ca(2+) current in rabbit carotid body glomus cells.
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Academic Article
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Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups.
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Academic Article
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Detection of oxygen sensing during intermittent hypoxia.
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Academic Article
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Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptors.
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Academic Article
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Impaired ventilatory acclimatization to hypoxia in mice lacking the immediate early gene fos B.
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Academic Article
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Cellular and molecular mechanisms associated with carotid body adaptations to chronic hypoxia.
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Academic Article
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Secretion of brain-derived neurotrophic factor from PC12 cells in response to oxidative stress requires autocrine dopamine signaling.
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Academic Article
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Regulation of gene expression by HIF-1.
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Academic Article
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Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia.
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Academic Article
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Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia.
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Academic Article
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Regulation of breathing by tissue oxygen: evidence from mutant mice with Presbyterian hemoglobinopathy.
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Academic Article
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Acute lung injury augments hypoxic ventilatory response in the absence of systemic hypoxemia.
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Academic Article
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5-HT evokes sensory long-term facilitation of rodent carotid body via activation of NADPH oxidase.
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Academic Article
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Altered carotid body function by intermittent hypoxia in neonates and adults: relevance to recurrent apneas.
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Academic Article
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Effect of adenosine on chemosensory activity of the cat aortic body.
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Academic Article
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Heterozygous HIF-1alpha deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia.
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Academic Article
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ROS signaling in systemic and cellular responses to chronic intermittent hypoxia.
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Academic Article
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Increased secretory capacity of mouse adrenal chromaffin cells by chronic intermittent hypoxia: involvement of protein kinase C.
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Academic Article
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Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR.
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Academic Article
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HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia.
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Academic Article
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Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.
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Academic Article
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Transcriptional responses to intermittent hypoxia.
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Academic Article
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Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception.
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Academic Article
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Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells.
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Academic Article
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Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities.
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Academic Article
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Role of substance P in hypercapnic excitation of carotid chemoreceptors.
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Academic Article
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Role of the vagal afferents in substance P-induced respiratory responses in anaesthetized rabbits.
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Academic Article
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Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing.
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Academic Article
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Pattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinases.
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Academic Article
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NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia.
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Academic Article
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Hypoxia inhibits maturation and trafficking of hERG K(+) channel protein: Role of Hsp90 and ROS.
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Academic Article
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Redox Pioneer: Professor Gregg L. Semenza.
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Academic Article
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O2 sensing at the mammalian carotid body: why multiple O2 sensors and multiple transmitters?
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Academic Article
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Long-term regulation of carotid body function: acclimatization and adaptation--invited article.
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Academic Article
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Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells.
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Academic Article
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Respiratory effects of N-methyl-D-aspartate on the ventrolateral medullary surface.
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Academic Article
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H2S mediates O2 sensing in the carotid body.
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Academic Article
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Sensing hypoxia: carotid body mechanisms and reflexes in health and disease.
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Academic Article
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NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats.
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Academic Article
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NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells.
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Academic Article
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Intermittent hypoxia augments acute hypoxic sensing via HIF-mediated ROS.
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Academic Article
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Cellular mechanisms associated with intermittent hypoxia.
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Academic Article
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Sensory plasticity of the carotid body: role of reactive oxygen species and physiological significance.
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Academic Article
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Pronounced depression by propofol on carotid body response to CO2 and K+-induced carotid body activation.
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Academic Article
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Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.
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Academic Article
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Hydrogen peroxide differentially affects activity in the pre-Bötzinger complex and hippocampus.
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Academic Article
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Involvement of ventral medullary surface in respiratory responses induced by 2,4-dinitrophenol.
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Academic Article
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Sympatho-adrenal activation by chronic intermittent hypoxia.
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Academic Article
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The role of hypoxia-inducible factors in oxygen sensing by the carotid body.
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Academic Article
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Hydrogen sulfide (H(2)S): a physiologic mediator of carotid body response to hypoxia.
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Academic Article
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Somatostatin in the control of respiration.
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Academic Article
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Respiratory and vasomotor effects of excitatory amino acid on ventral medullary surface.
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Academic Article
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Mitochondrial reactive oxygen species mediate hypoxic down-regulation of hERG channel protein.
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Academic Article
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Post-translational modification of proteins during intermittent hypoxia.
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Academic Article
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Comparison of the effects of hypercapnia on phrenic and hypoglossal activity in anesthetized decerebrate and decorticate animals.
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Academic Article
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Oxygen sensing in the body.
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Academic Article
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Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia.
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Academic Article
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Analysis of carotid chemoreceptor responses to substance P analogue in anaesthetized cats.
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Academic Article
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Carbon monoxide: a role in carotid body chemoreception.
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Academic Article
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Effect of arterial chemoreceptor stimulation: role of norepinephrine in hypoxic chemotransmission.
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Academic Article
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Inhibitory sympathetic action on the carotid body responses to sustained hypoxia.
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Academic Article
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Refinement of telemetry for measuring blood pressure in conscious rats.
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Academic Article
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Contrasting effects of intermittent and continuous hypoxia on low O(2) evoked catecholamine secretion from neonatal rat chromaffin cells.
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Academic Article
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Substance P and neurokinin A in the cat carotid body: localization, exogenous effects and changes in content in response to arterial pO2.
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Academic Article
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Substance P and mitochondrial oxygen consumption: evidence for a direct intracellular role for the peptide.
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Academic Article
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Enhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processing.
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Academic Article
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Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia.
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Academic Article
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Role of adenosine in hypoxic ventilatory depression.
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Academic Article
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Inhibition of expiratory muscle EMG and motor unit activity during augmented breaths in cats.
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Academic Article
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Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.
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Academic Article
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Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress.
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Academic Article
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Electrical stimulation of arterial and central chemosensory afferents at different times in the respiratory cycle of the cat: II. Responses of respiratory muscles and their motor nerves.
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Academic Article
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Respiratory and vasomotor responses to focal cooling of the ventral medullary surface (VMS) of the rat.
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Academic Article
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Naloxone enhances the response to hypercapnia of spinal and cranial respiratory nerves.
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Academic Article
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Hypoxia-inducible factor 2a (HIF-2a) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension.
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Academic Article
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Analysis of postinspiratory activity of phrenic motoneurons with chemical and vagal reflexes.
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Academic Article
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The effects of hypercapnia and cooling the ventral medullary surface on capsaicin induced respiratory reflexes.
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Academic Article
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Electrical stimulation of arterial and central chemosensory afferents at different times in the respiratory cycle of the cat: I. Ventilatory responses.
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Academic Article
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Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase.
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Academic Article
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Effect of substance P antagonist on the hypoxia-induced carotid chemoreceptor activity.
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Academic Article
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Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia.
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Academic Article
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NADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cells.
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Academic Article
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Tachykinin antagonists in carotid body responses to hypoxia and substance P in the rat.
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Academic Article
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Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat.
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Academic Article
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Novel role for reactive oxygen species as amplifiers of intermittent hypoxia. Focus on "Reactive oxygen species mediate central cardiorespiratory network responses to acute intermittent hypoxia".
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Academic Article
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Nitric oxide in the sensory function of the carotid body.
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Academic Article
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Effect of focal cooling of central chemosensitive areas on cerebral ischemic response.
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Academic Article
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Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.
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Academic Article
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Responses of hypoglossal and phrenic nerves to decreased respiratory drive in cats.
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Academic Article
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Low PO2 dependency of neutral endopeptidase and acetylcholinesterase activities of the rat carotid body.
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Academic Article
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Effect of distension of urinary bladder on blood pressure and respiration.
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Academic Article
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Role of substance P in rat carotid body responses to hypoxia and capsaicin.
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Academic Article
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Selective blockade of sensory response of the carotid body to hypoxia by NK-1 receptor antagonist CP-96,345.
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Academic Article
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Selective inhibition of the carotid body sensory response to hypoxia by the substance P receptor antagonist CP-96,345.
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Academic Article
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Intermittent hypoxia-mediated plasticity of acute O2 sensing requires altered red-ox regulation by HIF-1 and HIF-2.
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Academic Article
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Nitric oxide synthase activity in guinea pig ventricular myocytes is not involved in muscarinic inhibition of cAMP-regulated ion channels.
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Academic Article
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Gases as chemical messengers in the carotid body. Role of nitric oxide and carbon monoxide in chemoreception.
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Academic Article
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Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling.
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Academic Article
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Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body.
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Academic Article
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Ventral medullary surface inputs to cervical sympathetic respiratory oscillations.
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Academic Article
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Altered breathing pattern elicited by stimulation of abdominal visceral afferents.
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Academic Article
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Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase.
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Academic Article
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Cardiorespiratory changes induced by vertebral artery injection of sodium cyanide in cats.
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Academic Article
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L-type Ca(2+) channel activation regulates induction of c-fos transcription by hypoxia.
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Academic Article
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Chemosensing at the carotid body. Involvement of a HERG-like potassium current in glomus cells.
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Academic Article
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Peripheral chemosensitivity in mutant mice deficient in nitric oxide synthase.
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Academic Article
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Augmentation of calcium current by hypoxia in carotid body glomus cells.
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Academic Article
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Role of alpha 2-adrenergic receptors in the carotid body response to isocapnic hypoxia.
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Academic Article
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Role of nitric oxide in short-term potentiation and long-term facilitation: involvement of NO in breathing stability.
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Academic Article
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Activation of tyrosine hydroxylase by intermittent hypoxia: involvement of serine phosphorylation.
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Academic Article
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Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas.
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Academic Article
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Facilitation of dopamine and acetylcholine release by intermittent hypoxia in PC12 cells: involvement of calcium and reactive oxygen species.
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Academic Article
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Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity.
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Academic Article
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Attenuated outward potassium currents in carotid body glomus cells of heart failure rabbit: involvement of nitric oxide.
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Academic Article
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Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia.
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Academic Article
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Modulation of the hypoxic sensory response of the carotid body by 5-hydroxytryptamine: role of the 5-HT2 receptor.
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Academic Article
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Kv1.1 deletion augments the afferent hypoxic chemosensory pathway and respiration.
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Academic Article
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Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes.
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Academic Article
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Reactive oxygen species facilitate oxygen sensing.
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Academic Article
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Effect of adenosine on isolated and superfused cat carotid body activity.
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Academic Article
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Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia.
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Academic Article
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Influence of adrenaline and hypoxia on rat muscle receptors in vitro.
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Academic Article
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Neurotransmitters in the carotid body.
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Academic Article
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Influence of central chemoreceptor afferent inputs on respiratory muscle activity.
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Academic Article
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Respiratory and vasomotor influences of the ventrolateral medulla.
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Academic Article
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Integration of cardiorespiratory responses in the ventrolateral medulla.
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Academic Article
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Spinal termination of nociceptive afferent fibres from deep tissues in the cat.
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Academic Article
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Plasma renin activity and cardiovascular changes in patients with chronic bladder distension.
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Academic Article
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Developmental programming of O(2) sensing by neonatal intermittent hypoxia via epigenetic mechanisms.
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Academic Article
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Significance of pulmonary vagal afferents for respiratory muscle activity in the cat.
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Academic Article
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Peripheral chemoreceptors: function and plasticity of the carotid body.
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Academic Article
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Mutual antagonism between hypoxia-inducible factors 1a and 2a regulates oxygen sensing and cardio-respiratory homeostasis.
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Academic Article
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Regulation of hypoxia-inducible factor-a isoforms and redox state by carotid body neural activity in rats.
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Academic Article
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Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema.
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Academic Article
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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
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Academic Article
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Hypoxia-inducible factors regulate human and rat cystathionine ß-synthase gene expression.
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Academic Article
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Central and peripheral factors contributing to obstructive sleep apneas.
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Academic Article
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Impairment of pancreatic ß-cell function by chronic intermittent hypoxia.
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Academic Article
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CaV3.2 T-type Ca²? channels in H2S-mediated hypoxic response of the carotid body.
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Academic Article
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Intermittent hypoxia-induced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation.
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Academic Article
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Xanthine oxidase mediates hypoxia-inducible factor-2a degradation by intermittent hypoxia.
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Academic Article
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Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia.
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Academic Article
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Neuromolecular mechanisms mediating the effects of chronic intermittent hypoxia on adrenal medulla.
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Academic Article
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HIF-1a activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase.
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Academic Article
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The human carotid body releases acetylcholine, ATP and cytokines during hypoxia.
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Academic Article
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Epigenetic Regulation of Carotid Body Oxygen Sensing: Clinical Implications.
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Academic Article
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Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla.
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Academic Article
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Neural regulation of hypoxia-inducible factors and redox state drives the pathogenesis of hypertension in a rodent model of sleep apnea.
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Academic Article
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CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia.
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Academic Article
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Chronic Intermittent Hypoxia Alters Local Respiratory Circuit Function at the Level of the preBötzinger Complex.
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Academic Article
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Carotid body chemoreflex: a driver of autonomic abnormalities in sleep apnoea.
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Academic Article
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H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea.
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Academic Article
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Complementary roles of gasotransmitters CO and H2S in sleep apnea.
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Academic Article
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HIF-1a is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium.
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Academic Article
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Measurement of Sensory Nerve Activity from the Carotid Body.
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Academic Article
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The role of hypoxia-inducible factors in carotid body (patho) physiology.
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Academic Article
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Immunohistochemistry of the Carotid Body.
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Academic Article
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Therapeutic Targeting of the Carotid Body for Treating Sleep Apnea in a Pre-clinical Mouse Model.
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Academic Article
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DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity.
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Academic Article
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Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells.
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Grant
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Integrative Consequences of Intermittent Hypoxia
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Academic Article
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Long-term facilitation of catecholamine secretion from adrenal chromaffin cells of neonatal rats by chronic intermittent hypoxia.
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Academic Article
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Neural Activation of Molecular Circuitry in Intermittent Hypoxia.
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Academic Article
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Olfactory receptor 78 participates in carotid body response to a wide range of low O2 levels but not severe hypoxia.
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Academic Article
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Hypoxia-inducible factors and obstructive sleep apnea.
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Academic Article
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Hypoxia-inducible factor-1 mediates pancreatic ß-cell dysfunction by intermittent hypoxia.
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Academic Article
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Olfactory receptor 78 regulates erythropoietin and cardiorespiratory responses to hypobaric hypoxia.
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Academic Article
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Gaseous transmitter regulation of hypoxia-evoked catecholamine secretion from murine adrenal chromaffin cells.
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Academic Article
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Role of olfactory receptor78 in carotid body-dependent sympathetic activation and hypertension in murine models of chronic intermittent hypoxia.
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Academic Article
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Histone Deacetylase 5 Is an Early Epigenetic Regulator of Intermittent Hypoxia Induced Sympathetic Nerve Activation and Blood Pressure.
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Academic Article
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Lysine demethylase KDM6B regulates HIF-1a-mediated systemic and cellular responses to intermittent hypoxia.
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Academic Article
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Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release.
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Academic Article
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Carotid body responses to O2 and CO2 in hypoxia-tolerant naked mole rats.
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Academic Article
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Adaptive cardiorespiratory changes to chronic continuous and intermittent hypoxia.
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Academic Article
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Intermittent hypoxia inhibits epinephrine-induced transcriptional changes in human aortic endothelial cells.
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Academic Article
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Gasotransmitter modulation of hypoglossal motoneuron activity.
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Concept
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ERG1 Potassium Channel
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Concept
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Transcriptional Regulator ERG
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Concept
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Essential Hypertension
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Concept
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NAV1.5 Voltage-Gated Sodium Channel
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Academic Article
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Editorial: Vascular pathophysiology in hypoxia.
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Academic Article
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P300/CBP Regulates HIF-1-Dependent Sympathetic Activation and Hypertension by Intermittent Hypoxia.
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Academic Article
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Correction: Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells.
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Academic Article
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Transcriptomic Analysis of Postnatal Rat Carotid Body Development.
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